Glaucoma · Patient video

How can Pigment Dispersion Syndrome lead to Glaucoma?

Medically reviewed by Carl J. May Jr., MD · American Board of OphthalmologyLast updated June 2026
Transcript

Pigment dispersion syndrome is a condition that happens when pigment rubs off of the back of the iris of the eye when the fibers supporting the lens rub against it. This pigment is deposited in the trabecular meshwork of the eye, where the fluid drains out. Up to 50 percent of people with this condition can develop elevated eye pressure and glaucoma if the pigment decreases the outflow of fluid. This condition is more common in people that are nearsighted. Your doctor will perform a careful exam of the lens after your pupils are dilated to detect the subtle signs of exfoliation. Remember that caring for your eyesight begins with complete eye examinations. A comprehensive evaluation is the best way to detect eye conditions such as glaucoma early, so that it can be addressed before it develops into something more serious.

What’s in this video

In pigment dispersion syndrome, pigment flakes off the back of the iris and collects in the eye's drain — and up to half of people with it develop raised pressure or glaucoma. It's more common in nearsighted people, and a dilated exam helps us track it.

This page and video are for general patient education and are not a substitute for a medical examination, diagnosis, or treatment. Eye conditions vary by individual. For advice about your eyes, schedule an evaluation or call (717) 637-1919. In an emergency, call 911.

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