Glaucoma · Patient video

How does Pseudoexfoliation Syndrome lead to Glaucoma?

Medically reviewed by Carl J. May Jr., MD · American Board of OphthalmologyLast updated June 2026
Transcript

Pseudoexfoliation syndrome is a condition that is caused by tiny flakes that build up in the front of the eye. This fibrillar material is deposited on the the lens of the eye and also in the trabecular meshwork of the eye where the fluid drains out. In some patients this can block the outflow of the fluid in the eye, raising the eye pressure and causing glaucoma. Not all people with Pseudoexfoliation syndrome develop glaucoma. It is common for one eye to develop this condition earlier than the other eye, but both eyes are at risk for glaucoma if Pseudoexfoliation material is present. If you have Pseudoexfoliation syndrome, your chances of developing glaucoma are about six times higher than people who do not have it. Your doctor will perform a careful exam of the lens after your pupils are dilated to detect the subtle signs of Pseudoexfoliation. Remember that caring for your eyesight begins with complete eye examinations. A comprehensive evaluation is the best way to detect eye conditions such as glaucoma early, so that it can be addressed before it develops into something more serious.

What’s in this video

In pseudoexfoliation syndrome, flaky material collects inside the eye and can clog its drainage, raising pressure and making glaucoma about six times more likely. A dilated exam lets us detect it and keep a close watch on your eyes.

This page and video are for general patient education and are not a substitute for a medical examination, diagnosis, or treatment. Eye conditions vary by individual. For advice about your eyes, schedule an evaluation or call (717) 637-1919. In an emergency, call 911.

← All Glaucoma videos
§ 12Get Started

Ready to see
the world clearly?

Schedule a consultation with Dr. May today. Our team walks you through every step — from your first exam to your clearest day yet.

No-pressure consultations
CareCredit — 24-month no-interest financing
Serving Hanover, York & surrounding communities
Same medical team from consult through recovery

Contact the practice

Address250 Fame Ave, Suite 225
Hanover, PA 17331
Phone(717) 637-1919
Emailreception1@mayeyecare.com
Fax(223) 639-5010
Call to Schedule